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We could get through most situations providing we can preserve the lives of the ones we like. Using two separate drugs to shed pounds can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight loss and the people that go through it you should err along the side of caution and let the FDA do its job and demand some investigation be done in order that the public is aware of the side effects and hazards of the medications before we drive them. Keep in mind that drug companies come in business to generate income and that they would say almost anything to keep people on his or her medications. Researchers discovered that participants investing in this drug to get a year, lost excess weight within a month and have kept the weight off through the entire 56 weeks in the study. Contrave is often a combination with the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which can be made up of multiple active ingredient, that might make them far better and safer. Combo-pilling could be the newest fad or also the newest in the future under scrutiny and therefore it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills has become popular may be the fact that as of right now there are no long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug could also raise blood pressure level and heartrate, and really should not be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not be used in patients with uncontrolled high blood pressure, and also by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients on the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking. The most common adverse reactions reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.